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    Estimates of the mean heart rate adipex were considered by CHMP not to be necessarily the most relevant parameter (compared to e .
    adipex increase in heart rate in the highest percentile or increased proportion of subjects with > 10 bpm) The consequence of the sympathomimetic mechanism of action of Qsiva for CV outcome in long-term use remains a principle concern for CHMP in the absence of long-term CV outcome trial data .
    The supportive information on safety diet pills with adipex hydrochloride adipex drug test military adipex 37.5 without dr prescription of phentermine from the literature provided by the applicant was considered by CHMP to be very limited due to factors such as only retrospective, cohort studies submitted, absence of a reliable control group, etc .
    Although the amount of phentermine in the high dose of Qsiva is half of that currently licensed for use as a single agent in the US and the UK, the addition of topiramate was shown to increase adipex exposure to phentermine by 40% in the PK studies .
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    Psychiatric safety –Depression, anxiety and adipex cognitive impairment were more commonly reported in patients treated with Qsiva than placebo .
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